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Thamarai Schneiders focuses on the intrinsic mechanisms that contribute to the evolution of antibiotic resistance and the survival fitness of Gram-negative bacteria. Her research addresses critical questions about how bacteria resist antibiotics and evade the immune system. Specifically, she studies the hidden mechanisms that allow bacteria such as Klebsiella to cause serious infections by outsmarting human defenses against antibiotic therapy. A notable discovery in her research involves the role of the RamA protein, which modifies lipopolysaccharides that are components of the outer coating of Klebsiella, providing new insights into how these bacteria alter their survival strategies within the human host.
Centre Inflammation Research • Edinburgh
Leading research on antibiotic resistance mechanisms in Gram-negative bacteria.
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