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Dr. Thomas DeRaedt is an Assistant Professor in the Department of Pediatrics at the Perelman School of Medicine, University of Pennsylvania. He focuses on understanding the mechanisms of pediatric High Grade Gliomas and aims to develop novel therapies based on these insights. His lab employs advanced molecular analysis and creates accurate mouse models to study the molecular underpinnings of these tumors, particularly looking at the RAS pathway and its epigenetic regulators. DeRaedt's work is significant in the context of improving treatment options for pediatric gliomas, a group of tumors associated with poor survival rates. His research has inspired multiple ongoing clinical trials aiming to translate laboratory findings into effective treatments. He also explores new cellular therapies, including CAR-T therapy, and has demonstrated innovative approaches in delivering therapeutic agents. DeRaedt's dedication to bridging the gap between basic science and clinical application positions him as a leading figure in his field.
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