Dr. Thomas Eykyn

Biography

Thomas Eykyn studied undergraduate chemistry (MChem) at the University of Oxford and completed his PhD in solution state NMR methodology at the Université de Lausanne, Switzerland, under Geoffrey Bodenhausen. He undertook a two-year secondment to the École Normale Supérieure in Paris, where he developed applications for cross-polarization magnetization transfer in isotopically labelled spin-systems. His postdoctoral research at the University of Sydney with Philip Kuchel focused on novel NMR applications in biophysical studies of red blood cells and metabolic studies in living cells. Afterwards, he worked at the Institute of Cancer Research, contributing to the development of hyperpolarized 129Xe techniques and leading a program for hyperpolarized 13C metabolic imaging in cancer using dynamic nuclear polarization (DNP) with Martin Leach. This work achieved world-first applications for real-time cell measurements of pyruvate-lactate metabolism, enhancing the understanding of kinetics in therapeutic modulation. He is currently a Lecturer at King's College London, furthering NMR spectroscopic and hyperpolarized MRI metabolomic techniques to elucidate metabolic remodeling in heart, brain, and liver cancer. Eykyn has a keen interest in NMR methodology, pulse sequence design, and enzyme-mediated reaction processes. He serves on the Scientific Advisory Board of the Centre for Biomolecular Spectroscopy and is a committee member for the re-establishment of the MSci Chemistry Undergraduate program at King's. Eykyn is a Fellow of the Higher Education Academy and manages the 9.4T NMR/MRI facility in Biomedical Engineering.

Research Interests