Dr. Thomas Kepler

Biography

Thomas Kepler is an Emeritus Professor at Boston University's Chobanian & Avedisian School of Medicine. He holds a PhD from Brandeis University and a BA from the University of Massachusetts Boston. His research focuses on the development of computational tools and context systems-level experimentation to address critical questions in immunology and vaccine development. Kepler's work, particularly on B cells and antibodies, involves the genetic mechanisms through which these cells produce antibodies capable of binding specific molecules, thereby conferring long-term immunity. He collaborates with colleagues from Duke and Harvard Universities to apply computational methods in vaccination approaches that drive affinity maturation. This innovative research underpins vaccine development efforts in areas like HIV, influenza, and anthrax. He has been involved in various significant research projects and has contributed to multiple publications in his field of expertise.

Research Interests