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Thomas Melia is a professor in the Department of Cell Biology at Yale School of Medicine. His research focuses on macroautophagy, a cellular process critical for degrading and recycling cellular components in response to starvation. His work explores the mechanisms of autophagosome formation, including the dynamics of membrane interactions and the role of autophagy in various diseases such as neurodegeneration, heart disease, and cancer. His lab employs a combination of low-resolution cell-based assays and high-resolution imaging techniques, including electron cryo-microscopy, to reveal the complexities of membrane architecture and protein function during autophagy. Melia's contributions to the field are well-regarded, with extensive publication records detailing his research interests and findings in cell biology and lysosomal function.
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