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Thomas Douglas Petes is a distinguished professor in the Department of Molecular Genetics and Microbiology at Duke University, where he also leads the Petes Lab. His research primarily focuses on the mechanisms of mitotic recombination, genetic regulation of genome stability, and genetic instability associated with interstitial telomeric sequences. Petes' work utilizes the yeast Saccharomyces cerevisiae to explore the fundamental processes underlying DNA damage repair through mitotic recombination, significantly contributing to the understanding of how genomic integrity is maintained. He has developed advanced systems to detect mitotic crossovers and genome-wide mapping methods for UV-induced recombination events. His collaborations and studies have characterized chromosome alterations and the impact of DNA replication mutations in yeast. Additionally, Petes has received multiple grants from the National Institutes of Health for his extensive work on genome stability and recombination. He earned his Ph.D. from the University of Washington in 1973 and has held various prestigious positions, including serving as a chair for the Department of Molecular Genetics and Microbiology. His contributions offer valuable insights into the genetic foundations of cancer and hereditary diseases.
Department of Biomedical Engineering (MS program)