Dr. Thomas Roberts

Biography

Thomas McCoy Roberts, Ph.D., is a Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He serves as Co-Chairman of the Department of Cancer Biology at Dana-Farber Cancer Institute. Dr. Roberts received his PhD from Harvard University and completed a postdoctoral fellowship. His laboratory focuses on understanding the molecular mechanisms of signal transduction, particularly the role of activated tyrosine kinases in cancer therapy. Notably, his research on phosphoinositide 3 (PI3) kinase has advanced the understanding of its role in human cancer and has led to the development of specific inhibitors that target cancer-related isoforms. Dr. Roberts also pioneered studies on the regulation of serine/threonine kinase, Raf-1, and characterized its interactions with 14-3-3 proteins. Collaboratively, he has contributed to significant advancements in kinase inhibitor programs and the therapeutic strategies for certain cancers. His work has been instrumental in establishing the foundational knowledge required for the clinical application of isoform-specific inhibitors.

Research Interests

Experience