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Tianqing Peng is a professor in the Department of Pathology and Laboratory Medicine at Western University. His primary research focus is on understanding the mechanisms of myocardial dysfunction and injury in various pathological conditions, including diabetic cardiomyopathy and doxorubicin cardiotoxicity. He employs a wide range of approaches that encompass cellular and molecular biology, as well as in vivo physiology, to study the molecular mechanisms involved in myocardial dysfunction. His lab utilizes cultured cardiomyocytes and isolated whole hearts to investigate the significance of key genes and proteins in these processes. Currently, his research emphasizes the signaling pathways activated in cardiomyocytes in response to doxorubicin, a critical drug used in cancer treatment, aiming to develop strategies for prevention and treatment of associated cardiotoxic effects. Additionally, he is studying the molecular mechanisms underlying hyperglycemia and high levels of free fatty acids that lead to cardiomyocyte injuries, working towards developing therapeutic strategies to safeguard the heart against such injuries. His work also explores issues related to multiple organ failure in the context of sepsis.
Streams include Archaeology and Bioarchaeology, and Sociocultural Anthropology.