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Tim Corson’s research applies chemical biology approaches to clinical problems related to eye disease, notably neovascularization, which is the abnormal growth of blood vessels seen in conditions like age-related macular degeneration and diabetic retinopathy. His lab employs a wide variety of techniques, including high-throughput compound screening, novel compound development, and biochemical approaches to understand compound mechanisms of action. Moreover, Corson focuses on developing therapeutic targets for treating neovascular diseases through innovative solutions, shifting away from existing medications that are delivered via injections into the eye. He explores various protein targets relevant to disease and seeks to develop new therapies that could be administered in more manageable forms such as eye drops or tablets. Some of his notable research targets include ferrochelatase, APE1/Ref-1, and soluble epoxide hydrolase (sEH). His work not only addresses significant medical challenges but also contributes to the innovation of drug discovery and therapeutic approaches in ophthalmology.
Department of Sociology