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Tso-Pang Yao is a Professor in the Department of Pharmacology and Cancer Biology, with additional responsibilities in the Department of Radiation Oncology at Duke University. His research focuses on the regulatory functions of protein acetylation in cell signaling and human disease, particularly in the context of deacetylases and their potential as therapeutic targets in cancer treatment. Professor Yao's major research areas include aging and age-related diseases, mitochondrial biology, and cancer metabolism. His laboratory explores mechanisms underlying quality control in autophagy related to neurodegenerative diseases and the role of mitochondrial protein acetylation in metabolic adaptation. Notably, he has investigated the impact of HDAC6 in enforcing quality control autophagy, particularly in models of neurodegenerative disorders. He also examines the signaling pathways involving HDAC4 in skeletal muscle remodeling and neuromuscular diseases. Professor Yao has a Ph.D. from the University of California, San Diego, and has received multiple NIH grants for his research.
Duke University • Durham, NC
Professor in the Department of Pharmacology and Cancer Biology, also involved in the Department of Radiation Oncology.
Duke University • Durham, NC
Served as Associate Professor in the Department of Pharmacology and Cancer Biology.
Duke University • Durham, NC
Held a position as Assistant Research Professor in Radiation Oncology.
Duke University • Durham, NC
Worked as an Assistant Professor in the Department of Pharmacology and Cancer Biology.
Duke University • Durham, NC
Temporary Instructor in the Department of Pharmacology and Cancer Biology.
Department of Biomedical Engineering (MS program)