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The Aryal Laboratory specializes in mass spectrometry-based approaches to investigate the underlying mechanisms of senescence and aging at cellular and organism levels. The lab focuses on understanding the changes in the proteome and the dynamic changes in protein post-translational modifications that contribute to aging and aging-associated diseases, including cancer and neurodegenerative diseases. Recent publications highlight significant advancements in the field, such as the discovery of molecular signatures in neurodegenerative diseases through proteomic and phosphoproteomic analyses, as well as insights into protein functions mediated by TNF-α in hepatocytes. Dr. Aryal has been active in sharing research findings at various conferences, achieving notable accolades for student presentations and showcasing the lab's contributions to the understanding of brain aging and metabolic diseases. The lab continues to be engaged in collaborative efforts and publications that advance the knowledge of proteomic landscapes in complex conditions.
Oklahoma State University • Stillwater, OK
Leading research initiatives in proteomics and aging-related studies.