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Dr. Uriel Lopez-Sanchez is focused on the molecular mechanical basis of cell adhesion signaling, particularly in integrins-related receptors that orchestrate immune, developmental, and disease processes. His research utilizes single-molecule tools and organoid systems to uncover nanoscale conformational changes and force transmission, which significantly shapes multicellular organization and disease pathogenesis. Dr. Lopez-Sanchez received the Charles King Trust Postdoctoral Research Fellowship to support his work on the structural mechanisms underlying rolling adhesion activity of integrins such as α4β1 and α4β7.
Springer Lab • Cambridge, MA
Researching structural mechanisms of integrins in cell adhesion.