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Professor Vassilis Koronakis leads research focusing on bacterial toxin export and multidrug efflux in Gram-negative bacteria. His group investigates the structural and functional aspects of inner membrane translocases and the dynamics of TolC, a crucial element for substrate specificity in bacteria. His notable work includes determining the high-resolution structure of TolC through biochemical and biophysical methods. Koronakis's research also explores the mechanisms Salmonella utilizes to invade mammalian cells. His lab studies how pathogenic E. coli manipulate host cell signaling pathways to facilitate adhesion and cytoskeletal rearrangements. Additionally, his group is probing the complexities of cell movement and lipid-mediated signaling using advanced reconstitution techniques. Koronakis collaborates with a team of researchers and aims to address pressing questions in cell biology, particularly related to cellular signaling and pathogenesis.
Standard postgraduate requirements for Department of Politics and International Studies (POLIS) and related humanities departments.