Dr. Vassilis Pachnis

Professor

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Biography

Vassilis Pachnis is the Principal Group Leader at the Francis Crick Institute, focusing on the interplay between developmental biology and the nervous system. His research explores the organization, construction, and function of the enteric nervous system and its significant role in gastrointestinal health and disease. His lab is dedicated to understanding how networks of neurons and glial cells develop and maintain proper functionality over a lifespan. Researchers under his guidance are investigating the genetic and molecular signals that direct the development of the enteric nervous system during embryonic stages and promote healthy maturation into adulthood. Additionally, they are examining how disruptions in this system can lead to gastrointestinal disorders. Vassilis employs an array of advanced experimental strategies, including molecular genetic manipulations, microscopy, and bioinformatics, to unravel these complex interactions.

Research Interests

Requirements for Francis Crick Institute

Doctorate Program
Requirements
GPA Requirement
Required:3.3
Prerequisites
A first or upper second-class honours degree in a relevant subject (biological sciences, physics, chemistry, engineering, mathematics, or computer science). Appropriate research experience gained during or outside of a university degree.
Application Checklist
  • Online application form
  • Curriculum Vitae (PDF, max 2MB)
  • Personal statement (covering scientific interest, PhD motivation, and research experience)
  • Names and contact details of two academic/scientific referees
  • Details of university degree(s) and academic transcripts
  • Selection of up to three preferred PhD projects/research groups
Specialization Notes

The Francis Crick Institute does not have traditional 'departments' but operates via interdisciplinary research groups. Candidates apply to the 'Crick PhD Programme' and select specific research topics or labs (e.g., Cell Biology, Immunology, Cancer Research) that align with the listed department names. Students register with one of three partner universities: UCL, King's College London, or Imperial College London.