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Dr. Virginia Man-yee Lee is the John H. Ware 3rd Endowed Professor at the Perelman School of Medicine at the University of Pennsylvania. Her research expertise centers on understanding the pathological mechanisms associated with neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, frontotemporal lobar degeneration, and amyotrophic lateral sclerosis. Dr. Lee's work has been instrumental in uncovering how specific proteins, including tau and alpha-synuclein, aggregate in the brain, leading to neuronal dysfunction and cell death. Her laboratory employs a variety of research techniques such as protein biochemistry, cell and molecular biology, and the use of transgenic mouse models to investigate the underlying biological processes driving neurodegeneration. Through her findings, Dr. Lee aims to identify potential therapeutic targets for drug discovery and develop innovative treatments for these debilitating disorders.
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