Dr. Vivian Saridakis

Biography

Vivian Saridakis is an Associate Professor at York University in the Faculty of Science. Her research focuses on the biochemical role of deubiquitinating enzymes in regulating cellular processes, particularly the attachment of ubiquitin to target proteins and their subsequent degradation by the 26S proteasome. This area of study has significant implications for understanding the regulation of the cell cycle, stress responses, signal transduction, and DNA repair mechanisms. Saridakis has published extensively on deubiquitination and its importance in cellular function, highlighting the roles of ubiquitin-specific proteases (USPs) in the removal of ubiquitin from target proteins, which is crucial for various biological processes. Her work aims to provide a complete understanding of the ubiquitination and deubiquitination pathways and their impact on cellular regulation. Saridakis has contributed to significant publications, including studies on the structural mechanisms of USP7 and its interaction with various proteins, which has set the foundation for new therapeutic opportunities in cancer treatment.

Research Interests

Experience