Dr. Wei Mi

Biography

Wei Mi obtained a PhD in structural biology from Peking University. He pursued postdoctoral training at Purdue University, the University of Washington, and Harvard Medical School, where he joined the laboratory of Maofu Liao, focusing on using cryo-electron microscopy to determine the structures of ATP-binding cassette transporters in lipid bilayer environments. In 2019, he became an Associate Professor in the Department of Pharmacology at Yale School of Medicine. His research concentrates on the mechanisms by which membrane proteins regulate the synthesis of lipopolysaccharides (LPS) using genetic, biochemical, and structural approaches. He is particularly interested in understanding the regulation of LPS biogenesis in Escherichia coli and its implications for antibiotic development, notably in the context of combatting antibiotic resistance in Gram-negative bacteria.

Research Interests