Dr. Wei Mi

Biography

Wei Mi obtained his PhD degree in structural biology from Peking University, Beijing, China. He is fascinated by the structures of membrane proteins and received postdoctoral training at Purdue University, the University of Washington, and Harvard Medical School (HMS). At HMS, he joined the laboratory of Dr. Maofu Liao, where he used single particle cryo-electron microscopy (Cryo-EM) to determine the structures of ATP-binding cassette transporters in a lipid bilayer environment. In 2019, Dr. Mi joined the Department of Pharmacology at Yale University School of Medicine, focusing on dissecting the mechanisms of membrane proteins involved in lipopolysaccharide (LPS) synthesis regulation through genetic, biochemical, and structural approaches. His research addresses antibiotic resistance, a pressing public health challenge, particularly in Gram-negative bacteria, which possess unique outer membranes that contribute to antibiotic resistance. Dr. Mi's laboratory aims to elucidate the regulatory mechanisms in LPS biogenesis, contributing valuable insights for the development of novel antibiotics.

Research Interests

Awards