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Dr. Wentian Yang received his M.D. from Lanzhou University School of Medicine and a Ph.D. in Molecular Biology from Sichuan University School of Medicine in China. He completed post-doctoral training in cellular signal transduction and cancer biology under the guidance of Dr. Benjamin G. Neel at Harvard Medical School. His research focuses on bone and cartilage development and homeostasis, particularly the processes regulated by protein tyrosine kinases (PTKs) and phosphatases (PTPs) in both physiological and pathological conditions. Dr. Yang's work aims to translate basic science discoveries into therapeutic strategies for combating skeletal disorders. He employs various research strategies, including biochemical, biological, and histological analysis, to gain insights into the roles of PTKs and PTPs in musculoskeletal disorders. His ongoing research investigates the molecular mechanisms by which SHP2 modulates chondrogenesis and osteoclastogenesis, which are critical for bone health. Dr. Yang is also involved in several funded research projects that explore various aspects of hematopoietic stem cell biology and the regulation of osteoclasts. Throughout his career, he has actively contributed to the understanding of bone disorders and the development of new therapeutic approaches for their prevention and treatment.
Harvard Medical School, Beth Israel Deaconess Medical Center • Boston, MA
Investigated cellular signal transduction in cancer biology.
Cleveland Clinic Foundation Lerner Research Institute •
Focused on cancer biology.
Department: Department of Economics