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Professor Will Wood's research focuses on immune cell migration in the context of inflammation and infection. His laboratory utilizes Drosophila embryonic macrophages to investigate the mechanisms that allow immune cells to sense and polarize towards attractive sources such as wounds and apoptotic cells. The lab employs confocal live imaging and experimental genetics to uncover the signals that guide cell migration within complex three-dimensional environments. The study of cell movement is essential for understanding embryonic development and the failure of cells to migrate properly can result in severe abnormalities and disease. Hemocytes, large macrophage-like cells in Drosophila, play a critical role in patrolling tissues and responding to apoptotic corpses and pathogens. Understanding the regulation of hemocyte migration can provide insights into similar processes in vertebrate inflammation.
Centre Inflammation Research, University of Edinburgh • Edinburgh, UK
Leading research on immune cell migration and inflammation, focusing on Drosophila models.
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