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William C. Hahn is the William Rosenberg Professor of Medicine at Harvard University and the Dana-Farber Cancer Institute. His research primarily focuses on understanding the genetic alterations involved in cancer initiation and progression. Hahn's laboratory utilizes comprehensive tools such as RNAi and CRISPR-Cas9 to study the function of genetic alterations and their role in malignant transformation. His work includes the development of engineered cancer cell lines with defined genetic modifications to model human tumors and explore novel cancer therapies. Hahn has identified several new oncogenes and has made significant contributions towards the understanding of KRAS mutations, developing therapeutic strategies targeting these mutations. His research emphasizes the integration of functional genomic approaches and aims to translate genetic knowledge into effective cancer therapies.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).