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William Hwang is an Assistant Professor in the PhD Program in Biological Biomedical Sciences at Harvard University. His research focuses on understanding the complex interactions between tumors and their microenvironments, particularly how these dynamics influence oncological mechanisms. With a specific interest in pancreatic and gastrointestinal cancers, Dr. Hwang investigates the role of intratumoral nerves in cancer biology and therapeutic resistance. His work employs advanced techniques including high-resolution microscopy, single-cell spatial biology, and systems-level analyses to dissect the molecular and cellular interactions at play within tumor ecosystems. Dr. Hwang aims to pioneer studies in cancer neuroscience, uncovering fundamental biological insights that could lead to novel therapeutic interventions. Additionally, he explores the genetic and phenotypic factors that mediate therapeutic resistance, analyzing the roles of cell state plasticity and tumor-stromal interactions using innovative approaches such as spatial proteotranscriptomics and optogenetics. His work is pivotal in advancing our understanding of cancer pathophysiology and therapeutic development.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).