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William Schrage is a Professor at the University of Wisconsin–Madison, focusing on the vascular health dysfunction in humans, particularly in those who are typically 'healthy' but obese and insulin resistant. His research aims to define cardiovascular pathophysiology prior to overt clinical disease. Schrage investigates how exercise and environmental stressors can perturb physiology, unveiling subtle abnormalities that may not be present at rest. His work emphasizes the significant clinical promise of preventing cardiovascular damage related to diabetes over attempting to reverse it during later stages of life. His research areas include the mechanisms of vascular control in skeletal muscle circulation among obese and insulin resistant adults, as well as the study of cerebral vascular control in these individuals, where substantial subclinical impairments have been observed. Additionally, he has broadened his research goals to include the impact of type 1 diabetes on middle-aged adults, submitting a research proposal focused on the detection and progression of coronary and carotid atherosclerotic disease following a type 1 diabetes diagnosis. He emphasizes the importance of microvascular function in skin circulation, highlighting its clinical significance in diabetes care. Schrage's interdisciplinary expertise positions him to drive exciting discoveries in collaboration with endocrinologists, imaging experts, and neurologists.
Department: Department of Computer Sciences