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William Shih is a Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and the Department of Cancer Biology at the Dana-Farber Cancer Institute. He is a founding core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard. Shih holds an A.B. in Biochemical Sciences from Harvard and a Ph.D. from Stanford. His research explores the design principles of self-assembling molecular machines, primarily using structural DNA nanotechnology. Shih's key projects include developing DNA-based architectures through a novel tiling strategy that combines scaffold-dependence and size control in nanoconstructions. Additionally, he works on single-molecule analysis tools aimed at overcoming challenges in molecular identification and characterizing protein structures on a single-cell level. His work on DNA nanostructures also targets diagnostic and therapeutic applications, particularly in enhancing cancer vaccines through precise geometric control of molecular arrangements.
Harvard Medical School • Boston, MA
Teaching and conducting research in Biological Chemistry and Molecular Pharmacology.
Wyss Institute • Boston, MA
Contributing to research in Biologically Inspired Engineering.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.