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The Sun Lab investigates the fundamental mechanisms of tissue formation, maintenance, function and dysfunction, as well as regeneration and degeneration. Utilizing advanced genomic editing technologies, single-cell transcriptomics, epigenomics, and whole-tissue clearing, the lab aims to delineate the robust biological programs that dictate normal function and reveal the imperfections that initiate pathogenesis. The primary focus of research is the lung, a vital organ essential for survival. Investigations span fetal, pediatric, and adult diseases with the aim of explaining and curing these conditions. The lab employs disease modeling as a starting point to foster basic scientific discoveries related to developmental biology, stem cell biology, and the interactions between lung, immune, and neural circuits.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).