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Xing-Zhen Chen is a Professor in the Department of Physiology at the University of Alberta. With a research focus on transient receptor potential (TRP) channels, his laboratory investigates the role these superfamily cation channels play in sensory physiology, including responses to vision, pain, mechanical, and chemical sensations. His work encompasses the function and regulation of TRPP2 and other TRP channels, particularly as they relate to health conditions such as polycystic kidney disease, cancer, and calcium homeostasis disorders. Chen employs a variety of experimental methods, including molecular biology, electrophysiology, and CRISPR/Cas9 techniques, utilizing models such as cultured mammalian cells and zebrafish. He has authored several notable publications in high-impact journals, contributing significant insights into TRP channels' mechanisms that influence cellular and physiological functions.
University of Alberta • Edmonton, AB, Canada
Teaching and conducting research in the field of Physiology.
Department: Mechanical Engineering and Engineering Management