Dr. Xingde Li

Biography

Xingde Li is a Professor in the Johns Hopkins University departments of Biomedical Engineering, Electrical and Computer Engineering, and Oncology. His research is focused on advancing neurophotonics and translational biophotonics technologies. Li employs an interdisciplinary approach that integrates optics, electrical engineering, micro-nano technology, biology, and clinical medicine. His primary aim is to improve early disease detection, monitor treatment efficacy, and guide medical interventions. The technologies he develops facilitate fundamental research into disease mechanisms and brain function, as well as biomarker discovery and the integration of diagnostics with therapy (theranostics). His specific research interests include Optical Coherence Tomography (OCT), two-photon fiberscopy/endomicroscopy, multimodal imaging, and AI-assisted image acquisition and analysis for disease diagnosis and intervention guidance. Li has contributed to the development of label-free non-invasive optical histology techniques and is involved in research focusing on functional brain imaging in freely-behaving animals.

Research Interests