Dr. Ya Chi Ho

Biography

Ya-Chi Ho's research program focuses on understanding HIV-1 persistence and HIV-1-induced immune dysfunction using single-genome and single-cell approaches with clinical samples. Ho received her MD in 2002 from National Cheng Kung University and completed her internal medicine residency and infectious disease fellowship training in Taiwan in 2007. Following this, she practiced as an attending physician in infectious disease until 2008. Ho obtained her PhD from Johns Hopkins University School of Medicine in 2013, where she developed the full-length single-genome sequencing method, becoming a standard measurement for HIV-1 latent reservoir. After her postdoctoral work, she started her lab at Yale University in September 2017. Her current research includes understanding HIV-1-induced immune dysfunction and dynamics of HIV-infected cells using single-cell multi-omic techniques. Ho's lab employs molecular virology, genetics, and bioinformatics to explore mechanisms of HIV persistence and aims to develop potential cures. Her work has received substantial funding from the NIH, emphasizing the use of single-cell genomic approaches to investigate HIV.

Research Interests

Experience

Awards