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Yevgenya Grinblat is a Professor in the Department of Neuroscience at the University of Wisconsin–Madison. She obtained her Ph.D. from Harvard University in 1993. Her research focuses on the genetic control of cranial morphogenesis using zebrafish models to interrogate gene networks involved in cranial development in vertebrate embryos. Grinblat's studies have revealed critical insights into the conserved zinc-finger transcription factor Zic2, which is linked to congenital brain malformations such as holoprosencephaly. Her findings suggest that Zic2 plays pivotal roles in several key cell lineages that comprise the head, including the neural tube, eye structures, and craniofacial cartilages. Utilizing advanced tools and techniques such as CUT&RUN and in vivo proximity labeling, Grinblat aims to address significant gaps in knowledge concerning Zic2 and its cellular functions. Her contributions to understanding the genetic controls of brain and retinal development underscore the importance of this research in the context of developmental biology and medicine.
Department: Department of Computer Sciences