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Yi-Je (Jay) Chen is an Assistant Professor at UC Davis Health, specializing in pharmacology, with a strong focus on potassium channels and their implications in ischemic stroke and neuroinflammation. His research is centered on the molecular mechanisms of ion channels, particularly the calcium-activated K+ channel KCa3.1, which plays a critical role in ischemia-induced edema formation. He is investigating how these channels affect blood-brain barrier (BBB) dynamics and contribute to neuronal health during ischemic conditions. Through studies employing rodent models, pharmacological strategies, and advanced imaging techniques, he aims to develop new therapeutic strategies for preventing and treating edema as well as other complications associated with brain injuries. Dr. Chen's work also encompasses the physiological and pathological roles of ion channels in microglia and neutrophils during the early stages of ischemic stroke, seeking to discover novel pharmacological targets to mitigate neuroinflammation and enhance neuronal survival.
UC Davis Health • Davis, CA
Teaching and research in pharmacology, focusing on potassium channels and neuroinflammation.
Department of Computer Science. GRE is NOT required.