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Yi Zhang is a Fred S. Rosen Professor in Pediatrics and Genetics at Harvard University. His research lab focuses on understanding the role of epigenetic modifications in gene expression, stem cell reprogramming, germ cell development, and cancer drug resistance. Over the past decade, the lab has explored the dynamics of chromatin structure and the mechanisms by which these changes affect developmental processes. Specific projects have investigated various protein complexes, including the NuRD complex and histone methyltransferases, alongside innovative techniques such as live cell imaging and single-cell RNA sequencing. His team is dedicated to uncovering the intricate relationships between DNA methylation, histone modifications, and gene regulation during early embryogenesis, aiming to address critical challenges in cancer treatment and regenerative medicine.
Harvard University • Boston, MA
Leading research in epigenetic mechanisms in developmental biology and cancer.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).