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Yorgo Modis is a professor at the University of Cambridge, specializing in virology and immunology. His research focuses on the mechanisms by which viruses interact with host cell machinery to express and replicate their genes, emphasizing the innate immune response to viral infections. He investigates how cells distinguish between pathogenic viral RNAs and non-pathogenic endogenous nucleic acids while exploring the roles of transcriptional regulation and silencing of integrated viral DNA. Aiming to gain a mechanistic understanding at the molecular level, Modis employs a range of biophysical and biochemical techniques, including cryo-electron microscopy and X-ray crystallography, to reveal detailed atomic-level insights into virus-cell interactions. His work aims to identify novel strategies for immunomodulatory therapy and enhance our understanding of host-pathogen recognition and chromatin regulation.
Standard postgraduate requirements for Department of Politics and International Studies (POLIS) and related humanities departments.