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Zhen Chen is an Assistant Professor at Caltech in the Department of Biology and Biological Engineering. He completed his B.Sc. at Peking University in 2009, followed by an M.A. at Rice University in 2012. He earned his Ph.D. from Rockefeller University in 2019. In 2023, he was appointed as a Visiting Associate at Caltech and subsequently became an Assistant Professor. His research focuses on cell development, chromatin remodeling, flagellar biogenesis, and the dynamics of cytoskeleton perturbations associated with disease. Chen integrates cell biology with cryo-electron tomography to visualize the architecture of macromolecular machines within the native cellular environment at near-atomic resolution. His work aims to elucidate the molecular instructions that govern cellular processes and the structural organization that links to cellular function and developmental state. His innovative approaches have enabled the discovery of previously unknown molecular assemblies that enhance our understanding of complex cellular systems and diseases.
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