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Zhengrong Cui is a Professor in the College of Pharmacy at the University of Texas at Austin. His research interests focus on pharmaceutical formulation development and drug delivery systems. The Cui group explores innovative methods such as thin-film freeze-drying technology to create dry powders for biologics, including mRNA-lipid nanoparticles and monoclonal antibodies. They aim to enhance the thermostability of pharmaceutical products while enabling efficient delivery through pulmonary and intranasal routes due to unique aerosol properties. Cui's research also includes the synthesis and evaluation of antitumor compounds, particularly those inducing immunogenic cell death in tumors. Notable work includes the synthesis of 4-(N)-docosahexaenoyl 2’,2’-difluorodeoxycytidine, highlighted for its antitumor efficacy and potential in sensitizing immunologically ‘cold’ tumors for immunotherapy. His published research can be found in several peer-reviewed journals available through academic databases.
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