Dr. Li Huei Tsai

Biography

Li-Huei Tsai is a Professor and Director of the Picower Institute at the Massachusetts Institute of Technology (MIT). She obtained her Ph.D. from the University of Texas Southwestern Medical Center in Dallas and completed her postdoctoral training at Cold Spring Harbor Laboratories and Massachusetts General Hospital. Tsai became an Assistant Professor in Pathology at Harvard Medical School and was promoted to tenured Professor in 2002. She relocated to MIT in 2006. Tsai is an Investigator with the Howard Hughes Medical Institute from 1997 to 2013 and has received several prestigious honors, including being a Fellow of the American Association for the Advancement of Science and a Member of the National Academy of Medicine. Her research interests focus on elucidating the pathogenic mechanisms underlying neurological disorders that impact learning and memory, with a goal of identifying new therapeutic targets. Her lab employs a multidisciplinary approach, combining molecular biology, electrophysiology, computational biology, and bioengineering to study disease pathogenesis at the cellular systems level. This includes analyzing disease-associated changes through genomic, transcriptomic, and epigenomic analyses, as well as system-level manipulations in animal models to understand disease phenotypes.

Research Interests

Experience