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Xiaoxi Zhuang is a Professor in the Neuroscience Institute at the University of Chicago. Her research focuses on the molecular machinery underlying synaptic plasticity and information processing in the brain. She is especially interested in the synaptic mechanisms that support reinforcement learning and motor control. To investigate these topics, her lab employs a variety of techniques including mouse and fly genetics, optogenetics, animal learning paradigms, electrophysiology, and molecular biology. Among her notable contributions, Zhuang has explored strategies for reversing aberrant synaptic plasticity as a potential therapy for neurological and psychiatric disorders. She has published several impactful studies in prominent journals, highlighting her work on topics such as dopamine signaling, basal ganglia circuitry, and the genetic interactions affecting behavior and metabolism.
Department of Philosophy